How is Vitamin-E Thought to Play a Role in Reducing the Risk of Heart Disease?

According to a recent poll, almost 40% of American adults take dietary supplements on a weekly basis.

The majority of people who take vitamins for cardiovascular health do so because they include vitamin E.

How is Vitamin-E Thought to Play a Role in Reducing the Risk of Heart Disease?

The National Health and Nutrition Examination Survey found that vitamin E supplementation was utilised by 37% of adults.

11.3 percent of these people had vitamin E intakes of 400 IU or greater on a daily basis. Vitamin E was also used at higher levels.

In those with a history of cardiovascular illness, angina pectoris, stroke, or diabetes than in people without these problems.

Treatment of Heart Disease with Vitamin E

In humans, alpha-tocopherol is the most bioavailable form of vitamin E, and it has long been believed that its antioxidant characteristics make it an effective medication for preventing cardiovascular disease.

Vitamin E has been shown to inhibit protein kinase C activation, atherosclerotic lesions, smooth muscle cell proliferation.

And platelet adhesion and aggregation in animal models. Vitamin E therapy has also been demonstrated to improve endothelial function in human trials.

The Intake of Vitamin E-Rich Foods

It has been found that middle-aged and older men and women who eat a diet high in vitamin E have a reduced chance of developing coronary heart disease.

Vitamin E has not been shown to be effective in either primary or secondary prevention of cardiovascular disease in large-scale clinical research.

There is some evidence to suggest that using vitamin E supplements raises the risk of death from all causes, heart failure, and bleeding in the event of a stroke.

Consuming meals rich in antioxidant vitamins and other nutrients is recommended by the American Heart Association rather than using vitamin E tablets for the purpose of preventing cardiovascular disease.

Vitamin E Antioxidants Are Fat-Soluble

Vitamin E, a fat-soluble antioxidant found in nature, has been suggested as a treatment for primary and secondary prevention of cardiovascular (CV) events.

Although observational epidemiological studies have shown a protective association between higher vitamin E intake and a reduced risk of cardiovascular events.

This finding has not been confirmed in randomised controlled clinical trials. Although current medical consensus.

It holds that vitamin E supplements of sufficient doses are not useful in the treatment or prevention of cardiovascular disease.

New information is emerging that identifies a specific population for this treatment: patients with diabetes mellitus and the haptoglobin genotype 2-2.


Contrasted with placebo, vitamin E did not significantly reduce the risk of cardiovascular death or stroke (also known as a “cerebrovascular accident”).

Although vitamin doses varied and patient demographics were wide ranging, the same lack of benefit was observed across all of them. This study “does not support the routine use of vitamin E,” according to the CCF researchers.